Analyzing the Parkinson's disease clinical trial pipeline to facilitate patient collaboration in research.
The World Parkinson Coalition® is a unique organization filling a niche in the global Parkinson's community by bringing the full spectrum of community members together both in person at our triennial World Parkinson Congresses and virtually at our WPC Scientific Updates. Learn more at www.worldpdcoalition.org
By highlighting promising areas of research and where they are in the pipeline, the PDTrialTracker tool can help foster further collaboration between patients and researchers to accelerate the path to a cure. Insights gained through analysis of the pipeline can lead to development of action plans to help set research priorities, address roadblocks, increase awareness of recruitment and funding needs, improve the participant trial experience, and more.
compiled by PD research advocate Kevin McFarthing PhD
This listing includes Parkinson's therapies in development that may provide symptom relief or modify disease progression (slow, halt, or reverse progression). It includes 99 projects in the clinical stage and 126 in the research/pre-clinical stage, as of July 2, 2018. Feedback and updates can be emailed to kevin DOT mcfarthing AT innovationfixer DOT com
Suggestions for improving access to PD trial data in order to help facilitate trial awareness, recruitment, and research efforts:
This spreadsheet has 4 tabs/worksheets labeled: Phase 1 Trials, Phase 2 Trials, Phase 3 Trials, and Disease-Modifying Trials. The goal of the charts is to highlight key parameters and timelines for studies in the PD clinical trial pipeline to facilitate patient/researcher collaboration. Comments and feedback can be emailed to email@example.com.
compiled by PD research advocates Sue Buff and Gary Rafaloff
These documents provide an overview of disease-modifying therapies (therapies to slow, halt or reverse progression) currently in PD clinical trials (Phase 1, 2, 3), as well a partial listing of upcoming clinical trials. They include links for access to more extensive information about the studies.
Background and motivation
There are currently no approved neuroprotective/interventional drug treatments for Parkinson's disease which have been shown to slow, halt or reverse progression. However, there are over 60 clinical trials which are now active or in the planning stage. This review is for the benefit of patients who are trying to follow current research developments and who are trying to make decisions with regard to trial participation. We've tried to be as comprehensive as possible and provide all of the basic information needed prior to contacting a trial coordinator for more detailed information and a consent form. We would appreciate any information available on the listed trials, as well as those we may have missed. Updates can be emailed to firstname.lastname@example.org.