Analyzing the Parkinson's disease clinical trial pipeline to facilitate patient collaboration in research.

PDTrialTracker.info

See interventional trials page and observational studies page for more in-depth analysis of the PD clinical trial pipeline.


See trial participation page to view recruiting trial information via interactive map tools.


See research collaboration page to help facilitate patient/researcher collaboration efforts.

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Location of 261 active PD trials in the U.S.

(map source: ClinicalTrials.gov, 10/7/17)

Overview of

Active PD Clinical Trials Worldwide

Studies with multiple locations are included in each region containing locations.

Note:  Active PD trials include those:

i) currently recruiting, ii) not yet recruiting, iii) enrolling by invitation and

iv) in-progress, not recruiting. 

Location of 569 active PD trials worldwide

(map source: ClinicalTrials.gov, 10/7/17)

About PDTrialTracker.info


Parkinson's disease (PD) is a progressive neurological disorder affecting an estimated 1 to 1.5 million people in the United States and 4 to 7 million people worldwide.  


The goal of PDTrialTracker.info is to provide Parkinson's patients, families, researchers, health care providers, and other interested members of the PD community with analysis of ongoing PD clinical trials and observational studies throughout the world in order to:

  • understand the types of trials underway and where they are in the pipeline,
  • highlight the most promising avenues of research (e.g., particular disease modifying therapies, symptomatic treatments)
  • uncover roadblocks in the trial process and ways to address them (e.g., improving recruitment methods, enhancing clinical trial best practices),
  • promote accurate and timely sharing of trial information for ongoing and completed trials (e.g., within ClinicalTrials.gov),
  • facilitate greater collaboration between Parkinson's patients, families, researchers, and physicians to accelerate progress towards a cure.


Clinical Trial Data Source

Clinical trial and study data on PDTrialTracker.info are obtained from the ClinicalTrials.gov database,a web-based resource that provides information to the public, free of charge, on publicly and privately supported clinical studies on a wide range of diseases and conditions.  Launched in February 2000, ClinicalTrials.gov is maintained by the National Library of Medicine at the National Institutes of Health (NIH). See ClinicalTrials.gov overview


Clinical trial data available on ClinicalTrials.gov is submitted directly by each study's sponsor or principal investigator.  To date, over 240,000 studies from around the world have been listed on ClinicalTrials.gov.  This includes over 1700 Parkinson's disease trials/studies, with over 500 of these currently active.  


 









PDTrialTracker Analysis

PDTrialTracker monitors and analyzes Parkinson's disease clinical trials and observational studies that are in-progress, that is, i) currently recruiting, ii) active, but not yet recruiting, iii) enrolling by invitation or iv) active, not recruiting.  The analysis is presented in tabular and graphical formats to provide greater insight into the type and focus of trials underway. 


For example, trial data is filtered, categorized and displayed by study parameters such as:

- interventional vs. observational studies

- disease-modifying vs. symptom-treating therapies

- therapy being evaluated

- symptoms being targeted

- Phase 1 or Phase 2 or Phase 3, etc.

- study location (by medical center, by state, by country)

- trial target completion dates (e.g., 2017, 2018, etc.)


These types of filtered data views are presented in canned, out-of-the-box displays that can yield insights and suggest action plans to help streamline the trial process.


Taking Action

Insights and action plans developed through use of PDTrialTracker could foster further collaboration between patients and researchers.  A patient/researcher feedback loop (to be developed) could include presentation of patient recommendations (gathered through PDTrialTracker surveys, petitions, online forum, etc.) at movement disorder research conferences, for example.


Specific types of patient feedback could include:

  • inputs on research priorities.
  • recommendations for improving the participant trial experience.
  • request to adopt a clinical trial naming convention that includes a trial's ClinicalTrials.gov ID number (NCT number) in all trial communications with the public (media, recruiting efforts, etc.) so patients can easily access that trial's available data on ClinicalTrials.gov.
  • request for keeping trial data up-to-date on ClinicalTrials.gov.
  • request for submission of trial results to ClinicalTrials.gov for all completed trials.
  • request for updates on enrollment status for actively recruiting trials that urgently need participants to stay on schedule or that have barriers to enrollment preventing study progress.